Radiologically isolated syndrome and clinically isolated syndrome

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Radiologically isolated syndrome in children

The phenomenon of radiologically isolated syndrome (RIS) in MS represents a key topic of clinical significance. Adults with RIS are asymptomatic at the time of presentation, but have brain MRI scans containing incidental findings highly suggestive of MS, and, importantly, a high rate—59%—of subsequent emergence of newMRI changes and a 5-year risk of clinical events of 34%. Of note, almost 10% o...

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Radiologically isolated syndrome in children

Objective: To describe clinical and radiologic outcomes of children with incidental findings on neuroimaging suggestive of CNS demyelination (termed “radiologically isolated syndrome” or RIS). Methods: Clinical and radiologic data were obtained from a historical cohort of children with no symptoms of demyelinating disease who had MRI scans that met the 2010 MRI criteria for dissemination in spa...

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Radiologically Isolated Syndrome: An Overview

The use of brain magnetic resonance imaging (MRI) for evaluation of neurological disorders has increased in the past two decades. This has led to an increased detection of incidental findings on brain MRI. The most common of these asymptomatic abnormalities are white matter lesions that are interpreted as demyelinating based on radiological criteria. However, in the absence of associated clinic...

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Gray Matter Involvement in Radiologically Isolated Syndrome

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ژورنال

عنوان ژورنال: Clinical and Experimental Neuroimmunology

سال: 2017

ISSN: 1759-1961

DOI: 10.1111/cen3.12346